Selected pyridinol analogues of the experimental neuroprotective drug idebenone have been synthesized and evaluated as antioxidants capable of preserving mitochondrial function. The compounds, having a different redox core but the same side chain as idebenone, exhibited a range of potencies, reflecting differences in their structures.

Read More: Analysis of the structural and mechanistic factors in antioxidants that preserve mitochondrial function and confer cytoprotection