BACKGROUND AND PURPOSE:
In Friedreich's ataxia (FRDA), frataxin deficiency results in iron redistribution in the dentate nuclei (DNC). Clusters of iron cause inhomogeneities in a magnetic field and result in a reduction in T2 relaxation time (T2).
Read More: Dentate nuclei T2 relaxometry is a reliable neuroimaging marker in Friedreich's ataxia
